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MEDICAL HUMANITIES LECTURE SERIES
ETHICAL CONSIDERATIONS OF USING HEALTHY HUMAN SUBJECTS
IN TRANSCRANIAL MAGNETIC STIMULATION (TMS) RESEARCH
Leslie Jones
School of Medicine, USC
April 5, 2006
Wednesday, 12:00pm-1:30pm
Sumwalt College, Room 102
Research on the potential treatment value of TMS on patients with illnesses
such as depression started over 20 years ago. TMS has not yet been FDA
approved for any clinical treatment, but its use as a tool to study brain
function in healthy human subjects has skyrocketed in recent years. A
brief review of the neurophysiology of the brain will be given as a
bckground to understanding what is known about the effects of TMS on the
normal brain. An overview of the clinical uses that have been tested will
be presented followed by a more in-depth look at the literature from animal
studies on the myriad effects of TMS on the brain. The ethical question we
will examine is, why, given the extensive literature on the many long-term
effects of TMS on animal brains, do researchers continue to expose the
brains of healthy subjects to this electrically invasive tool for no other
purpose than to satisfy their own scientific curiosity? How do the
"benefits outweigh the risks" for these ! subjects.
Note: A lunch will be available for the first ten people who confirm
their attendance to Sheala Riley. Sheala can be reached at
sriley@gwm.sc.edu or by phone at 777-1543. She will need a reply by the end
of Friday (3/31/06), since she has to give notice on the meals a couple of
days in advance. If you're interested, please contact Sheala to say that
you will come, give your name, and whether you want chicken and rice or
vegetable lasagna.
For further information, please contact George Khushf (KhushfG@gwm.sc.edu),
who organizes the Medical Humanities Seminar Series.
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